The implication from RAS/RAF/ERK signaling pathway increased activation in epirubicin treated triple negative breast cancer
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The implication from RAS/RAF/ERK signaling pathway increased activation in epirubicin treated triple negative breast cancer
Background Triple negative breast cancer (TNBC) is not sensitive to RAS/RAF/ERK signaling pathway (ERK pathway) targeting therapy, due to the absence of excessive activation of ERK pathway. However, the kinase cascades might be activated after chemotherapy in TNBC. Here we aimed to predict whether ERK pathway targeting therapy could be used as an adjuvant therapy in TNBC. Methods Within onlin...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2017
ISSN: 1949-2553
DOI: 10.18632/oncotarget.22604